Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib
Author(s) -
Ali Jabbari,
Zhenpeng Dai,
Luzhou Xing,
Jane Cerise,
Yuval Ramot,
Yackov Berkun,
Gina A. Montealegre Sanchez,
Raphaela GoldbachMansky,
Angela M. Christiano,
Raphael Clynes,
Abraham Zlotogorski
Publication year - 2015
Publication title -
ebiomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.596
H-Index - 63
ISSN - 2352-3964
DOI - 10.1016/j.ebiom.2015.02.015
Subject(s) - medicine , alopecia areata , concomitant , in vivo , hair loss , clinical trial , dermatology , microbiology and biotechnology , biology
Alopecia areata (AA) is an autoimmune disease resulting in hair loss with devastating psychosocial consequences. Despite its high prevalence, there are no FDA-approved treatments for AA. Prior studies have identified a prominent interferon signature in AA, which signals through JAK molecules.
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