Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water | Zendy

Allan H. Smith | Zendy; Guillermo Marshall | Zendy; Yan Yuan | Zendy; Craig Steinmaus | Zendy; Jane Liaw | Zendy; Martyn T. Smith | Zendy; Lily Wood | Zendy; Marissa Heirich | Zendy; Rebecca Fritzemeier | Zendy; Mark D. Pegram | Zendy; Catterina Ferreccio | Zendy

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Rapid Reduction in Breast Cancer Mortality With Inorganic Arsenic in Drinking Water

Author(s) -

Allan H. Smith,

Guillermo Marshall,

Yan Yuan,

Craig Steinmaus,

Jane Liaw,

Martyn T. Smith,

Lily Wood,

Marissa Heirich,

Rebecca Fritzemeier,

Mark D. Pegram,

Catterina Ferreccio

Publication year - 2014

Publication title -

ebiomedicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.596

H-Index - 63

ISSN - 2352-3964

DOI - 10.1016/j.ebiom.2014.10.005

Subject(s) - arsenic trioxide , arsenic , breast cancer , medicine , cancer , mortality rate , acute promyelocytic leukemia , oncology , physiology , cancer research , chemistry , biochemistry , retinoic acid , organic chemistry , gene

Arsenic trioxide is effective in treating promyelocytic leukemia, and laboratory studies demonstrate that arsenic trioxide causes apoptosis of human breast cancer cells. Region II in northern Chile experienced very high concentrations of inorganic arsenic in drinking water, especially in the main city Antofagasta from 1958 until an arsenic removal plant was installed in 1970.

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