Data supporting that miR-92a suppresses angiogenic activity of adipose-derived mesenchymal stromal cells by down-regulating hepatocyte growth factor | Zendy

Anastasia Efimenko | Zendy; Georgy Sagaradze | Zendy; Zhanna Akopyan | Zendy; Tatiana Lopatina | Zendy; Natalia Kalinina | Zendy

Open Access

Data supporting that miR-92a suppresses angiogenic activity of adipose-derived mesenchymal stromal cells by down-regulating hepatocyte growth factor

Author(s) -

Anastasia Efimenko,

Georgy Sagaradze,

Zhanna Akopyan,

Tatiana Lopatina,

Natalia Kalinina

Publication year - 2015

Publication title -

data in brief

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.122

H-Index - 30

ISSN - 2352-3409

DOI - 10.1016/j.dib.2015.12.021

Subject(s) - mesenchymal stem cell , hepatocyte growth factor , adipose tissue , stromal cell , microbiology and biotechnology , microrna , transfection , chemistry , biology , cancer research , biochemistry , gene , receptor

This article contains the full list of miRNAs expressed in cultured mesenchymal stromal cells, which were isolated from human adipose tissue. We provide here data regarding the effect of miR-92a overexpression on MSCs viability and cellular content of HGF and angiopoietin-1. These are followed by the data regarding the effect of conditioned medium of MSC transfected with pre-miR-92a, anti-miR-92a or scramble oligos on HUVEC viability as well as their tube formation efficiency. We also demonstrate here data regarding the effect of extracellular vesicle depletion from MSCs conditioned medium on its ability to stimulate the tube formation by HUVEC. Data interpretation and discussion can be found in Kalinina et al. (2015) [1].

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