Epithelial sodium channels (ENaC) produce extracellular positive DC potentials in the retinal neuroepithelium
Author(s) -
Masayuki Yamashita
Publication year - 2015
Publication title -
data in brief
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 30
ISSN - 2352-3409
DOI - 10.1016/j.dib.2015.11.068
Subject(s) - extracellular , retinal , epithelial sodium channel , chemistry , microbiology and biotechnology , neuroepithelial cell , sodium , biophysics , biology , biochemistry , organic chemistry , embryonic stem cell , gene
Positive DC (direct current) potentials were measured in the extracellular space in the retinal neuroepithelium of chick embryos. The positive DC potential was suppressed by amiloride, a blocker for epithelial Na(+) channels (ENaC). Amiloride also decreased the resistance of the extracellular space as measured by passing a constant current through a microelectrode. The positive DC potential is necessary for the guidance of retinal ganglion cell axons [1].
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