Data in support of in vivo studies of silk based gold nano-composite conduits for functional peripheral nerve regeneration | Zendy

Suradip Das | Zendy; Manav Sharma | Zendy; Dhiren Saharia | Zendy; Kushal Konwar Sarma | Zendy; Monalisa Goswami Sarma | Zendy; Bibhuti Bhusan Borthakur | Zendy; Utpal Bora | Zendy

Open Access

Data in support of in vivo studies of silk based gold nano-composite conduits for functional peripheral nerve regeneration

Author(s) -

Suradip Das,

Manav Sharma,

Dhiren Saharia,

Kushal Konwar Sarma,

Monalisa Goswami Sarma,

Bibhuti Bhusan Borthakur,

Utpal Bora

Publication year - 2015

Publication title -

data in brief

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.122

H-Index - 30

ISSN - 2352-3409

DOI - 10.1016/j.dib.2015.05.020

Subject(s) - regeneration (biology) , nerve guidance conduit , in vivo , sciatic nerve , biocompatibility , biomedical engineering , schwann cell , materials science , peripheral nerve , peripheral nerve injury , adhesion , anatomy , medicine , microbiology and biotechnology , biology , composite material , metallurgy

In the present data article we report the in vitro and in vivo biocompatibility of fabricated nerve conduits described in Das et al. [1]. Green synthesised gold nanoparticles (GNPs) were evaluated for their cytotoxicity in rat Schwann cells (SCTM41). We also describe herein the adhesion and proliferation of Schwann cells over the nanofibrous scaffolds. Methods describing surgical implantation of conduits in a rat sciatic nerve injury model, confirming its accurate implantation as well as the porosity and swelling tendency of the nerve conduits are illustrated in the various figures and graphs.

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