Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis | Zendy

Jyothi Padiadpu | Zendy; Priyanka Baloni | Zendy; Nagasuma Chandra | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Gene expression profiles of wild-type and isoniazid-resistant strains of Mycobacterium smegmatis

Author(s) -

Jyothi Padiadpu,

Priyanka Baloni,

Nagasuma Chandra

Publication year - 2015

Publication title -

data in brief

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.122

H-Index - 30

ISSN - 2352-3409

DOI - 10.1016/j.dib.2015.05.006

Subject(s) - mycobacterium smegmatis , gene , biology , isoniazid , strain (injury) , accession number (library science) , wild type , mycobacterium , gene expression , fold change , genetics , microbiology and biotechnology , mycobacterium tuberculosis , bacteria , mutant , medicine , tuberculosis , pathology , anatomy , genbank

The global variations in the gene expression pattern of drug treated (½X) and laboratory evolved drug-resistant strains (2XR and 4XR) of Mycobacterium smegmatis were obtained and compared with the M. smegmatis mc(2) 155 (WT) strain. The genes exhibiting two-fold change and p-value <0.05 under the treated conditions have been considered as differentially expressed genes (DEGs). Overall, the numbers of DEGs observed are 1529 in ½X (596-up, 933-down), 1381 (899-up, 482-down) in 2XR and 716 in 4XR (267-up, 449-down) conditions. The data is publicly available through the GEO database with accession number GSE64132.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research