Comparative secretome analysis of rat stomach under different nutritional status | Zendy

Lucía L. Senín | Zendy; Arturo Roca-Rivada | Zendy; Cecilia Castelao | Zendy; Jana Alonso | Zendy; Cintia Folgueira | Zendy; Felipe F. Casanueva | Zendy; María Pardo | Zendy; Luísa M. Seoane | Zendy

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Comparative secretome analysis of rat stomach under different nutritional status

Author(s) -

Lucía L. Senín,

Arturo Roca-Rivada,

Cecilia Castelao,

Jana Alonso,

Cintia Folgueira,

Felipe F. Casanueva,

María Pardo,

Luísa M. Seoane

Publication year - 2015

Publication title -

data in brief

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.122

H-Index - 30

ISSN - 2352-3409

DOI - 10.1016/j.dib.2015.01.002

Subject(s) - stomach , ghrelin , explant culture , endocrine system , medicine , identification (biology) , bioinformatics , gastroenterology , biology , physiology , biochemistry , hormone , in vitro , botany

The fact that gastric surgery is at the moment the most effective treatment to fight against obesity highlights the relevance of gastric derived proteins as potential targets to treat this pathology. Taking advantage of a previously established gastric explant model for endocrine studies, the proteomic analysis of gastric secretome was performed. To validate this gastric explant system for proteomic analysis, the identification of ghrelin, a classical gastric derived peptide, was performed by MS. In addition, the differential analysis of gastric secretomes under differential nutritional status (control feeding vs fasting vs re-feeding) was performed. The MS identified proteins are showed in the present manuscript. The data supplied in this article is related to the research article entitled "Comparative secretome analysis of rat stomach under different nutritional status" [1].

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