z-logo
open-access-imgOpen Access
Data from a proteomic analysis of colonic fibroblasts secretomes
Author(s) -
Sun-Xia Chen,
XiaoEn Xu,
Xiaoqing Wang,
ShuJian Cui,
Leilei Xu,
Ying-Hua Jiang,
Yang Zhang,
Haibo Yan,
Qian Zhang,
Jie Qiao,
Pengyuan Yang,
Feng Liu
Publication year - 2014
Publication title -
data in brief
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.122
H-Index - 30
ISSN - 2352-3409
DOI - 10.1016/j.dib.2014.08.003
Subject(s) - fibroblast , colorectal cancer , cancer associated fibroblasts , cancer research , biology , cancer , chemistry , cell culture , microbiology and biotechnology , tumor microenvironment , tumor cells , genetics
The tumor cell proliferation, migration and invasion were influenced by the interaction between the cancer cells and their microenvironment. In current study, we established two pairs of the primary fibroblast cultures from colorectal adenocarcinoma tissues and the normal counterparts and identified 227 proteins in the colonic fibroblast secretomes; half of these proteins were novel. The mass spectrometry data and analyzed results presented here provide novel insights into the molecular characteristics and modulatory role of colon cancer associated fibroblasts. The data is related to "Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation" by Chen et al. [1].

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom