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Development and internal validation of multivariable prediction models for biochemical failure after MRI-guided focal salvage high-dose-rate brachytherapy for radiorecurrent prostate cancer
Author(s) -
T. Willigenburg,
Marieke van Son,
Sandrine M.G. van de Pol,
Wietse S.C. Eppinga,
J J W Lagendijk,
Hans C.J. de Boer,
Marinus A. Moerland,
Jochem R.N. van der Voort van Zyp,
Max Peters
Publication year - 2021
Publication title -
clinical and translational radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.336
H-Index - 15
ISSN - 2405-6308
DOI - 10.1016/j.ctro.2021.06.005
Subject(s) - brachytherapy , medicine , nomogram , prostate cancer , salvage therapy , proportional hazards model , prostatectomy , urology , nuclear medicine , radiation therapy , oncology , surgery , cancer , chemotherapy
Magnetic resonance-guided focal salvage high-dose-rate brachytherapy (FS-HDR-BT) for radiorecurrent prostate cancer (PCa) shows low toxicity rates. However, biochemical failure (BF) after treatment occurs frequently. We developed two prediction models for BF (Phoenix definition) with the aim of enhancing patient counselling before FS-HDR-BT and during follow-up.

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