Open AccessEstimated clinical benefit of combining highly conformal target volumes with Volumetric-Modulated Arc Therapy (VMAT) versus conventional flank irradiation in pediatric renal tumors
Author(s) -
Joeri Mul,
Enrica Seravalli,
Mirjam Bosman,
Cornelis P. van de Ven,
Annemieke S. Littooij,
Martine van Grotel,
Marry M. van den HeuvelEibrink,
Geert O. Janssens
Publication year - 2021
Publication title -
clinical and translational radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.336
H-Index - 15
ISSN - 2405-6308
DOI - 10.1016/j.ctro.2021.04.007
Subject(s) - flank , medicine , nuclear medicine , pancreas , radiation therapy , kidney , irradiation , cancer , radiology , anatomy , physics , nuclear physics
For decades, Anterior-Posterior/Posterior-Anterior (AP/PA) photon beams were standard-of-care for flank irradiation in children with renal cancer. Recently, highly conformal flank target volumes were defined correcting for postoperative organ shift and intra-fraction motion.By radiotherapy treatment plan comparison, this study aims to estimate the clinical benefits and potential risks of combining highly conformal target volumes with Volumetric-Modulated Arc Therapy (VMAT) versus conventional target volumes with AP/PA beams for flank irradiation.
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