Impact of suboptimal dosimetric coverage of pretherapeutic 18F-FDG PET/CT hotspots on outcome in patients with locally advanced cervical cancer treated with chemoradiotherapy followed by brachytherapy | Zendy

François Lucia | Zendy; Vincent Bourbonne | Zendy; Dorothy M. Gujral | Zendy; Gurvan Dissaux | Zendy; O. Miranda | Zendy; M. Mauguen | Zendy; Olivier Pradier | Zendy; Ronan Abgral | Zendy; Ulrike Schick | Zendy

Open Access

Impact of suboptimal dosimetric coverage of pretherapeutic 18F-FDG PET/CT hotspots on outcome in patients with locally advanced cervical cancer treated with chemoradiotherapy followed by brachytherapy

Author(s) -

François Lucia,

Vincent Bourbonne,

Dorothy M. Gujral,

Gurvan Dissaux,

O. Miranda,

M. Mauguen,

Olivier Pradier,

Ronan Abgral,

Ulrike Schick

Publication year - 2020

Publication title -

clinical and translational radiation oncology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.336

H-Index - 15

ISSN - 2405-6308

DOI - 10.1016/j.ctro.2020.05.004

Subject(s) - medicine , brachytherapy , cervical cancer , nuclear medicine , radiation therapy , chemoradiotherapy , positron emission tomography , radiation treatment planning , radiology , cancer

Areas of high uptake on pre-treatment 18 F-fluorodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT), denoted as "hotspots", have been identified as preferential sites of local relapse in locally advanced cervical cancer (LACC). The purpose of this study was to analyze the dosimetric coverage of these hotspots with high dose-rate brachytherapy (BT).

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