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Methodology for tissue sample collection within a translational sub-study of the CHHiP trial (CRUK/06/016), a large randomised phase III trial in localised prostate cancer
Author(s) -
Anna Wilkins,
Christine Stuttle,
Shama Hassan,
Claire Blanchard,
Clare Cruickshank,
Clare Griffin,
Jake Probert,
Catherine M. Corbishley,
Chris Parker,
David P. Dearnaley,
Emma Hall
Publication year - 2018
Publication title -
clinical and translational radiation oncology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.336
H-Index - 15
ISSN - 2405-6308
DOI - 10.1016/j.ctro.2018.02.002
Subject(s) - medicine , clinical trial , prostate , radiation therapy , prostate cancer , randomized controlled trial , translational research , cancer , medical physics , surgery , pathology
This article presents the methodology for tissue sample collection in Trans-CHHiP, the main translational study within the CHHiP (Conventional or Hypofractionated High dose intensity modulated radiotherapy in Prostate cancer, ISRCTN 97182923) trial. The CHHiP trial randomised 3216 men with localised prostate cancer to 3 different radiotherapy fractionation schedules. Trans-CHHiP aims to identify biomarkers of fraction sensitivity.

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