ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress | Zendy

Martin H. Neumann | Zendy; Sebastian Bender | Zendy; Thomas Krahn | Zendy; Thomas Schlange | Zendy

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ctDNA and CTCs in Liquid Biopsy – Current Status and Where We Need to Progress

Author(s) -

Martin H. Neumann,

Sebastian Bender,

Thomas Krahn,

Thomas Schlange

Publication year - 2018

Publication title -

computational and structural biotechnology journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.908

H-Index - 45

ISSN - 2001-0370

DOI - 10.1016/j.csbj.2018.05.002

Subject(s) - liquid biopsy , workflow , circulating tumor dna , current (fluid) , focus (optics) , circulating tumor cell , biopsy , computational biology , computer science , data science , medicine , biology , cancer , physics , database , optics , thermodynamics , metastasis

We discuss the current status of liquid biopsy and its advantages and challenges with a focus on pre-analytical sample handling, technologies and workflows. The potential of circulating tumor cells and circulating tumor DNA is pointed out and an overview of corresponding technologies is given.

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