Clinical experience with adalimumab in anti-TNF-naïve patients with ulcerative colitis

Dear Sir,Both medications and surgery have been used to treat ulcerative colitis (UC).1,2 Treatment with anti-TNF has shown to be effective in UC resistant to steroid or immunomodulator treatments.3 In this sense, the European Commission has recently approved adalimumab for the treatment of moderately to severely active UC in adult patients who have had an inadequate response to conventional therapy.We present a retrospective analysis of nine anti-TNF-naive patients with UC in whom adalimumab was administered as compassionate use …