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Anti-TNFα therapy early improves hemodynamics in local intestinal and extraintestinal circulations in active Crohn's disease
Author(s) -
Philippe Bonnin,
Jessica Coelho,
Marc Pocard,
Bernard Lévy,
Philippe Marteau
Publication year - 2012
Publication title -
journal of crohn s and colitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.277
H-Index - 80
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1016/j.crohns.2012.07.002
Subject(s) - medicine , hemodynamics , gastroenterology , fibrinogen , sma* , crohn's disease , blood flow , cardiology , endocrinology , disease , mathematics , combinatorics
Active Crohn's disease affects intestine but may alter other locations as eyes vasculature. Previous studies provide evidence of elevated blood flow velocities (BFv) and volume (BFV) in superior mesenteric artery (SMA). We prospectively studied hemodynamics in feeding arteries of bowel and eyes before and 2 weeks after treatment induction with anti-TNFα.

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