Open AccessTissue factor exposing microparticles in inflammatory bowel disease
Author(s) -
Julia Palkovits,
Gottfried Novacek,
Marietta Kollars,
Gregor Hron,
W. Osterode,
Peter Quehenberger,
Paul A. Kyrle,
Harald Vogelsang,
Walter Reinisch,
Pavol Papay,
Ansgar Weltermann
Publication year - 2012
Publication title -
journal of crohn s and colitis
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 3.277
H-Index - 80
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1016/j.crohns.2012.05.016
Subject(s) - medicine , tissue factor , inflammatory bowel disease , ulcerative colitis , pathogenesis , crohn's disease , interquartile range , coagulation , gastroenterology , immunology , d dimer , platelet activation , inflammation , c reactive protein , platelet , disease
Circulating procoagulant microparticles (MPs) are thought to be involved in the pathogenesis of venous thromboembolism in patients with inflammatory bowel disease (IBD). However, the exposure of tissue factor, the primary initiator of coagulation activation, on microparticles (TF(+)MPs) and its association with hemostasis activation has not yet been studied in IBD patients.
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