Open AccessOral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: Case report and review of the literature
Author(s) -
Filipe VilasBoas,
Fernando Magro,
Rui Balhau,
José Manuel Lopes,
Francisco Beça,
Catarina Eloy,
Susana Lopes,
Guilherme Macedo
Publication year - 2012
Publication title -
journal of crohn s and colitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.277
H-Index - 80
eISSN - 1876-4479
pISSN - 1873-9946
DOI - 10.1016/j.crohns.2012.03.004
Subject(s) - azathioprine , medicine , crohn's disease , basal cell , disease , lesion , biopsy , gastroenterology , cancer , dermatology , surgery
Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is well recognized and there are concerns that this may also be true for inflammatory bowel disease patients. We report a case of a 33-year-old Caucasian woman with Crohn's disease treated with azathioprine for 9 years who developed an ulcerated lesion at the right superior retromolar trigone. Biopsy specimen revealed a squamous cell carcinoma.
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