Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis | Zendy

Yavuz Beyazıt | Zendy; Seyfettin Köklü | Zendy; Adnan Taş | Zendy; Tuğrul Pürnak | Zendy; Abdurrahim Sayılır | Zendy; Mevlüt Kurt | Zendy; Turan Turhan | Zendy; Tuğrul Çelik | Zendy; Burak Suvak | Zendy; Serkan Torun | Zendy; Erdem Akbal | Zendy

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Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis

Author(s) -

Yavuz Beyazıt,

Seyfettin Köklü,

Adnan Taş,

Tuğrul Pürnak,

Abdurrahim Sayılır,

Mevlüt Kurt,

Turan Turhan,

Tuğrul Çelik,

Burak Suvak,

Serkan Torun,

Erdem Akbal

Publication year - 2011

Publication title -

journal of crohn s and colitis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.277

H-Index - 80

eISSN - 1876-4479

pISSN - 1873-9946

DOI - 10.1016/j.crohns.2011.07.010

Subject(s) - ulcerative colitis , adenosine deaminase , gastroenterology , medicine , erythrocyte sedimentation rate , inflammation , pathophysiology , adenosine , colitis , immunology , disease

Ulcerative colitis (UC) is a chronic inflammatory disease characterized by recurrent inflammation and ulcerations of colonic mucosa and an inappropriate and delayed healing. Adenosine deaminase (ADA) is a cytoplasmic enzyme involved in the catabolism of purine bases, capable of catalyzing the deamination of adenosine, forming inosine in the result process. Although ADA has been shown to increase in several inflammatory conditions, there are no literature data indicating an alteration in UC.

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