Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection
Author(s) -
Sinu P. John,
Anju Singh,
Jing Sun,
Makheni Jean Pierre,
Lulwah Alsalih,
Crystal C. Lipsey,
Ziann Traore,
Shenavia Balcom-Luker,
Clinton J. Bradfield,
Jian Song,
Tovah E. Markowitz,
Margery Smelkinson,
Marc Ferrer,
Iain D. C. Fraser
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.111441
Subject(s) - syk , lipopolysaccharide , tumor necrosis factor alpha , rutaecarpine , kinase , cytokine , biology , macrophage , microbiology and biotechnology , cytokine storm , immunology , pharmacology , chemistry , tyrosine kinase , medicine , signal transduction , biochemistry , in vitro , covid-19 , disease , pathology , infectious disease (medical specialty)
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