Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex
Author(s) -
Xiaoping Wu,
Alexander A. Sosunov,
Wudu Lado,
Jia Jie Teoh,
Ahrom Ham,
Hongyu Li,
Osama AlDalahmah,
Brian J.A. Gill,
Ottavio Arancio,
Catherine A. Schevon,
Wayne N. Frankel,
Guy M. McKhann,
David Sulzer,
James E. Goldman,
Guomei Tang
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.111085
Subject(s) - epileptogenesis , neuroscience , tsc1 , tuberous sclerosis , astrogliosis , tsc2 , biology , glutamatergic , epilepsy , pyramidal cell , neurotransmission , pi3k/akt/mtor pathway , hippocampus , pathology , glutamate receptor , microbiology and biotechnology , medicine , central nervous system , signal transduction , receptor , genetics
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