KS10076, a chelator for redox-active metal ions, induces ROS-mediated STAT3 degradation in autophagic cell death and eliminates ALDH1+ stem cells
Author(s) -
Jaehee Kim,
Areum Park,
Jieon Hwang,
Xianghua Zhao,
Jaesung Kwak,
Hyun Woo Kim,
Minhee Ku,
Jaemoon Yang,
Tae Il Kim,
KyuSung Jeong,
Uyeong Choi,
Hyuk Lee,
Sang Joon Shin
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.111077
Subject(s) - cancer cell , reactive oxygen species , superoxide , microbiology and biotechnology , chemistry , programmed cell death , cancer stem cell , intracellular , pro oxidant , cancer research , apoptosis , biology , biochemistry , stem cell , cancer , genetics , enzyme
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