Open AccessPGE2-EP2/EP4 signaling elicits immunosuppression by driving the mregDC-Treg axis in inflammatory tumor microenvironment
Author(s) -
Dean Thumkeo,
Siwakorn Punyawatthananukool,
Somsak Prasongtanakij,
Ryuma Matsuura,
Kentaro Arima,
Huan Nie,
Rie Yamamoto,
Naohiro Aoyama,
Hisao Hamaguchi,
Shingo Sugahara,
Shinobu Takeda,
Varodom Charoensawan,
Atsushi Tanaka,
Shimon Sakaguchi,
Shuh Narumiya
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.110914
Subject(s) - inflammation , immunosuppression , tumor microenvironment , immune system , cancer research , immunology , biology , signal transduction , prostaglandin e2 receptor , microbiology and biotechnology , receptor , biochemistry , agonist
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