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Sustained Trem2 stabilization accelerates microglia heterogeneity and Aβ pathology in a mouse model of Alzheimer’s disease
Author(s) -
Rahul Dhandapani,
Marilisa Neri,
Mario Bernhard,
Irena Brzak,
Tatjana Schweizer,
Stefan Rudin,
Stefanie Joller,
Ramon Berth,
Jasmin Kernen,
Aneuhaus,
Annick Waldt,
Rachel Cuttat,
Ulrike Naumann,
Caroline Gubser Keller,
Guglielmo Roma,
Dominik Feuerbach,
Derya R. Shimshek,
Ulf Neumann,
F. Gasparini,
Ivan Galimberti
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.110883
Subject(s) - trem2 , microglia , neuroinflammation , adam10 , genetically modified mouse , transmembrane protein , biology , alzheimer's disease , microbiology and biotechnology , receptor , transgene , inflammation , immunology , neuroscience , pathology , disease , medicine , biochemistry , metalloproteinase , gene , matrix metalloproteinase , disintegrin

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