Open AccessALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function
Author(s) -
Desiree M. Baron,
Adam R. Fenton,
Sara Sáez-Atiénzar,
Anthony Giampetruzzi,
Aparna Sreeram,
Shankaracharya,
Pamela Keagle,
Victoria R. Doocy,
Nathan J. Smith,
Eric W. Danielson,
Megan Andresano,
Mary C. McCormack,
Jaqueline Garcia,
Valérie Bercier,
Ludo Van Den Bosch,
Jonathan R. Brent,
Claudia Fallini,
Bryan J. Traynor,
Erika L.F. Holzbaur,
John E. Landers
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.110598
Subject(s) - gain of function , function (biology) , mutation , genetics , biology , chemistry , microbiology and biotechnology , business , gene
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