Open AccessMutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy
Author(s) -
Nicole M. Sayles,
Nneka Southwell,
Kevin McAvoy,
Kihwan Kim,
Alba Pesini,
Corey J. Anderson,
Catarina M. Quinzii,
Suzanne M. Cloonan,
Hibiki Kawamata,
Giovanni Manfredi
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.110475
Subject(s) - proteostasis , mitochondrion , biology , mitochondrial biogenesis , bioenergetics , mitochondrial dna , microbiology and biotechnology , oxidative stress , mitophagy , cardiomyopathy , biogenesis , genetics , autophagy , biochemistry , gene , medicine , apoptosis , heart failure
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