Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells | Zendy

Fraser Johnson | Zendy; John R. Ferrarone | Zendy; Alvin Liu | Zendy; Christina Brandstädter | Zendy; Ravi S. N. Munuganti | Zendy; Dylan Farnsworth | Zendy; Daniel Lu | Zendy; Jennifer Luu | Zendy; Tianna S. Sihota | Zendy; Sophie Jansen | Zendy; Amy Nagelberg | Zendy; Rocky Shi | Zendy; Giovanni C. Forcina | Zendy; Xu Zhang | Zendy; Grace Cheng | Zendy; Sandra E. Spencer Miko | Zendy; Georgia de Rappard-Yuswack | Zendy; Poul H. Sorensen | Zendy; Scott J. Dixon | Zendy; Udayan Guha | Zendy; Katja Becker | Zendy; Hakim Djaballah | Zendy; Romel Somwar | Zendy; Harold Varmus | Zendy; Gregg B. Morin | Zendy; William W. Lockwood | Zendy

Open Access

Characterization of a small molecule inhibitor of disulfide reductases that induces oxidative stress and lethality in lung cancer cells

Author(s) -

Fraser Johnson,

John R. Ferrarone,

Alvin Liu,

Christina Brandstädter,

Ravi S. N. Munuganti,

Dylan Farnsworth,

Daniel Lu,

Jennifer Luu,

Tianna S. Sihota,

Sophie Jansen,

Amy Nagelberg,

Rocky Shi,

Giovanni C. Forcina,

Xu Zhang,

Grace Cheng,

Sandra E. Spencer Miko,

Georgia de Rappard-Yuswack,

Poul H. Sorensen,

Scott J. Dixon,

Udayan Guha,

Katja Becker,

Hakim Djaballah,

Romel Somwar,

Harold Varmus,

Gregg B. Morin,

William W. Lockwood

Publication year - 2022

Publication title -

cell reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.264

H-Index - 154

eISSN - 2639-1856

pISSN - 2211-1247

DOI - 10.1016/j.celrep.2022.110343

Subject(s) - lethality , oxidative stress , synthetic lethality , small molecule , chemistry , cancer research , disulfide bond , lung cancer , cancer cell , cancer , microbiology and biotechnology , biochemistry , medicine , biology , toxicology , pathology , dna repair , gene

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