Nucleic acid delivery of immune-focused SARS-CoV-2 nanoparticles drives rapid and potent immunogenicity capable of single-dose protection
Author(s) -
Kylie M. Konrath,
Kevin Liaw,
Yuanhan Wu,
Xizhou Zhu,
Susanne N. Walker,
Ziyang Xu,
Katherine Schultheis,
Neethu Chokkalingam,
Himanshi Chawla,
Jianqiu Du,
Nicholas J. Tursi,
Alan Moore,
Jared AdolfBryfogle,
Mansi Purwar,
Emma L. Reuschel,
Drew Frase,
Matthew Sullivan,
Benjamin Fry,
Igor Maricic,
Viviane M. Andrade,
Christel Iffland,
Max Crispin,
Kate E. Broderick,
Laurent Humeau,
Ami Patel,
Trevor R.F. Smith,
Jesper Pallesen,
David B. Weiner,
Daniel W. Kulp
Publication year - 2022
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2022.110318
Subject(s) - immunogenicity , virology , antibody , epitope , neutralizing antibody , immune system , glycan , biology , antigen , coronavirus , dna vaccination , antigenicity , immunization , immunology , virus , medicine , covid-19 , infectious disease (medical specialty) , microbiology and biotechnology , glycoprotein , disease , pathology
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