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Species-selective targeting of pathogens revealed by the atypical structure and active site of Trypanosoma cruzi histone deacetylase DAC2
Author(s) -
Martin Marek,
Elizabeth RamosMorales,
Gisele Fernanda Assine Picchi-Constante,
Theresa Bayer,
Cariorström,
Daniel Herp,
Policarpo A. Sales-Junior,
Eloise Pavão Guerra-Slompo,
Kristin Hausmann,
Alokta Chakrabarti,
T.B. Shaik,
Annika Merz,
Edouard Troesch,
Matthias Schmidt,
Samuel Goldenberg,
Raymond J. Pierce,
Marina de Moraes Mourão,
Manfred Jung,
Johan Schultz,
Wolfgang Sippl,
Nilson Ivo Tonin Zanchin,
Christophe Romier
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.110129
Subject(s) - biology , histone deacetylase , trypanosoma cruzi , histone , acetylation , microbiology and biotechnology , computational biology , genetics , parasite hosting , dna , world wide web , computer science , gene

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