Open AccessA patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors
Author(s) -
Gururaj Shivange,
Tanmoy Mondal,
Evan Lyerly,
Sanchita Bhatnagar,
Charles N. Landen,
Shivani Reddy,
Jonathan Kim,
Britney Doan,
Paula Riddle,
Jogender TushirSingh
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109953
Subject(s) - ectodomain , antibody , receptor , ligand (biochemistry) , cancer research , function (biology) , apoptosis , blockade , chemistry , microbiology and biotechnology , biology , immunology , biochemistry
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