Open AccessLoss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis
Author(s) -
Shanshan Duan,
Loredana Moro,
Rui Qu,
Daniele Simoneschi,
Hyunwoo Cho,
Shaowen Jiang,
HuiYong Zhao,
Qing Chang,
Elisa de Stanchina,
Arnaldo Arbini,
Michele Pagano
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109870
Subject(s) - ubiquitin ligase , prostate cancer , mapk/erk pathway , ubiquitin , cancer research , chemistry , protein kinase b , pi3k/akt/mtor pathway , carcinogenesis , degradation (telecommunications) , prostate , signal transduction , cancer , medicine , computer science , biochemistry , gene , telecommunications
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