Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males
Author(s) -
Emily M. Walker,
Jeeyeon Cha,
Xin Tong,
Min Guo,
Jinhua Liu,
Sophia Yu,
Donato Iacovazzo,
Franck MauvaisJarvis,
Sarah E. Flanagan,
Márta Korbonits,
John M. Stafford,
David A. Jacobson,
Roland Stein
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109813
Subject(s) - senescence , biology , endocrinology , medicine , islet , missense mutation , mutation , phenotype , diabetes mellitus , telomere , dna damage , transcription factor , gene , genetics , dna
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