Open AccessOrganoid-based drug screening reveals neddylation as therapeutic target for malignant rhabdoid tumors
Author(s) -
Camilla Calandrini,
Sander R. van Hooff,
Irene Paassen,
Dilara Ayyildiz,
Sepide Derakhshan,
M. Emmy M. Dolman,
Karin P.S. Langenberg,
Marieke van de Ven,
Cecilia de Heus,
Nalan Liv,
Marcel Kool,
Ronald R. de Krijger,
Godelieve A.M. Tytgat,
Marry M. van den HeuvelEibrink,
Jan J. Molenaar,
Jarno Drost
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109568
Subject(s) - neddylation , organoid , cancer research , downregulation and upregulation , in vivo , drug , targeted therapy , biology , medicine , cancer , pharmacology , microbiology and biotechnology , ubiquitin , gene , ubiquitin ligase , biochemistry
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