Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity
Author(s) -
Avery J. Lam,
David Lin,
Jana Gillies,
Prakruti Uday,
Anne M. Pesenacker,
Michael S. Kobor,
Megan K. Levings
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109494
Subject(s) - foxp3 , biology , crispr , genome editing , transcription factor , transgene , gene , dna methylation , immune system , immunology , genetics , computational biology , gene expression
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