Open AccessParadoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells
Author(s) -
Perry W.E. Spratt,
Ryan P.D. Alexander,
Roy BenShalom,
Atehsa Sahagun,
Henry Kyoung,
Caroline M. Keeshen,
Stephan Sanders,
Kevin J. Bender
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109483
Subject(s) - nav1 , neocortex , sodium channel , excitatory postsynaptic potential , neuroscience , loss function , pyramidal cell , potassium channel , patch clamp , epilepsy , biology , electrophysiology , chemistry , biophysics , sodium , gene , inhibitory postsynaptic potential , phenotype , genetics , hippocampal formation , organic chemistry
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