Open AccessThe glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
Author(s) -
Chengxian Xu,
Shaogang Sun,
Travis S. Johnson,
Rong Qi,
Siyuan Zhang,
Jie Zhang,
Kai Yang
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109235
Subject(s) - gpx4 , lipid peroxidation , immunity , treg cell , peroxidase , immunology , glutathione , chemistry , glutathione peroxidase , immune system , biology , enzyme , t cell , biochemistry , il 2 receptor
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