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α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology
Author(s) -
Morgan G. Stykel,
Kayla Humphries,
Evelyn Rose Kamski-Hennekam,
Brodie Buchner-Duby,
Natalie Porte-Trachsel,
Tammy Ryan,
Carla Coackley,
Vladimir V. Bamm,
George Harauz,
Scott D. Ryan
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.109099
Subject(s) - endomembrane system , microbiology and biotechnology , endosome , proteostasis , mutant , alpha synuclein , biology , exocytosis , induced pluripotent stem cell , microvesicles , chemistry , parkinson's disease , biochemistry , intracellular , golgi apparatus , secretion , endoplasmic reticulum , medicine , microrna , embryonic stem cell , disease , pathology , gene

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