Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis | Zendy

Nisha Raj | Zendy; Zachary T. McEachin | Zendy; William Harousseau | Zendy; Ying Zhou | Zendy; Feiran Zhang | Zendy; Megan E. Merritt-Garza | Zendy; J. Matthew Taliaferro | Zendy; Magdalena Kalinowska | Zendy; Samuele Marro | Zendy; Chadwick M. Hales | Zendy; Elizabeth BerryKravis | Zendy; Marisol WolfOchoa | Zendy; Verónica MartínezCerdeño | Zendy; Marius Wernig | Zendy; Lu Chen | Zendy; Eric Klann | Zendy; Stephen T. Warren | Zendy; Peng Jin | Zendy; Zhexing Wen | Zendy; Gary J. Bassell | Zendy

Open Access

Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis

Author(s) -

Nisha Raj,

Zachary T. McEachin,

William Harousseau,

Ying Zhou,

Feiran Zhang,

Megan E. Merritt-Garza,

J. Matthew Taliaferro,

Magdalena Kalinowska,

Samuele Marro,

Chadwick M. Hales,

Elizabeth BerryKravis,

Marisol WolfOchoa,

Verónica MartínezCerdeño,

Marius Wernig,

Lu Chen,

Eric Klann,

Stephen T. Warren,

Peng Jin,

Zhexing Wen,

Gary J. Bassell

Publication year - 2021

Publication title -

cell reports

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 6.264

H-Index - 154

eISSN - 2639-1856

pISSN - 2211-1247

DOI - 10.1016/j.celrep.2021.108991

Subject(s) - neurogenesis , neural stem cell , fmr1 , fragile x syndrome , biology , translation (biology) , microbiology and biotechnology , pi3k/akt/mtor pathway , induced pluripotent stem cell , cell growth , progenitor cell , neurosphere , gene silencing , rna binding protein , cellular differentiation , stem cell , messenger rna , signal transduction , embryonic stem cell , genetics , adult stem cell , gene , fragile x

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