UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction
Author(s) -
Benjamin L. Zaepfel,
Zhe Zhang,
Kirstin Maulding,
Alyssa N. Coyne,
Weiwei Cheng,
Lindsey R. Hayes,
Thomas E. Lloyd,
Shuying Sun,
Jeffrey D. Rothstein
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108925
Subject(s) - c9orf72 , microbiology and biotechnology , neurotoxicity , biology , nonsense mediated decay , induced pluripotent stem cell , context (archaeology) , neuroprotection , neurodegeneration , rna , chemistry , neuroscience , trinucleotide repeat expansion , genetics , embryonic stem cell , toxicity , gene , medicine , paleontology , allele , disease , organic chemistry , rna splicing , pathology
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