Open AccessPI3K-Akt-mTORC1-S6K1/2 axis controls Th17 differentiation by regulating Gfi1 expression and nuclear translocation of RORγ
Author(s) -
Yutaka Kurebayashi,
Shigenori Nagai,
Ai Ikejiri,
Masashi Ohtani,
Kenji Ichiyama,
Yukiko Baba,
Taketo Yamada,
Shohei Egami,
Takayuki Hoshii,
Atsushi Hirao,
Satoshi Matsuda,
Shigeo Koyasu
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108886
Subject(s) - p70 s6 kinase 1 , mtorc1 , pi3k/akt/mtor pathway , protein kinase b , microbiology and biotechnology , downregulation and upregulation , chemistry , cancer research , phosphorylation , biology , signal transduction , biochemistry , gene
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