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Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice
Author(s) -
Jennifer E. Kay,
Joshua J. Corrigan,
Amanda L. Armijo,
Ilana S. Nazari,
Ishwar N. Kohale,
Dorothea K. Torous,
Svetlana L. Avlasevich,
Robert G. Croy,
Dushan N. Wadduwage,
Sebastian E. Carrasco,
Stephen D. Dertinger,
Forest M. White,
John M. Essigmann,
Leona D. Samson,
Bevin P. Engelward
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108864
Subject(s) - dna damage , base excision repair , dna repair , nitrosamine , dna glycosylase , synthetic lethality , carcinogen , cancer , cytotoxicity , dna , biology , dna replication , chemistry , cancer research , microbiology and biotechnology , genetics , in vitro

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