Open AccessPDK4 dictates metabolic resistance to ferroptosis by suppressing pyruvate oxidation and fatty acid synthesis
Author(s) -
Xinxin Song,
Jiao Liu,
Feimei Kuang,
Xin Chen,
Herbert J. Zeh,
Rui Kang,
Guido Kroemer,
Yangchun Xie,
Daolin Tang
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108767
Subject(s) - pdk4 , chemistry , beta oxidation , pyruvate dehydrogenase complex , biochemistry , glycolysis , resistance (ecology) , fatty acid , microbiology and biotechnology , metabolism , biology , enzyme , ecology
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