Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling
Author(s) -
Hao Wang,
Wei Hou,
Aldeb Perera,
Carlee Bettler,
Jordan R. Beach,
Xianzhong Ding,
Jun Li,
Mitchell F. Denning,
Asha Dhanarajan,
Scott J. Cotler,
Cara Joyce,
Jun Yin,
Fowsiyo Ahmed,
Lewis R. Roberts,
Wei Qiu
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108765
Subject(s) - cancer research , hepatocellular carcinoma , eph receptor a2 , protein kinase b , stat3 , signal transduction , in vivo , tumor initiation , biology , medicine , cancer , carcinogenesis , microbiology and biotechnology , receptor tyrosine kinase
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