Open AccessAn acetyl-histone vulnerability in PI3K/AKT inhibition-resistant cancers is targetable by both BET and HDAC inhibitors
Author(s) -
Di Wu,
Yuqian Yan,
Ting Wei,
Zhenqing Ye,
YuTian Xiao,
Yunqian Pan,
Jacob J. Orme,
Dejie Wang,
Liguo Wang,
Shancheng Ren,
Haojie Huang
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2021.108744
Subject(s) - bromodomain , acetylation , protein kinase b , pi3k/akt/mtor pathway , brd4 , histone , histone deacetylase , cancer research , biology , histone h3 , chemistry , biochemistry , phosphorylation , gene , signal transduction
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