Open AccessSmall Molecule SARM1 Inhibitors Recapitulate the SARM1−/− Phenotype and Allow Recovery of a Metastable Pool of Axons Fated to Degenerate
Author(s) -
Robert Hughes,
Todd Bosanac,
Xianrong Mao,
Thomas M. Engber,
Aaron DiAntonio,
Jeffrey Milbrandt,
Rajesh Devraj,
Raul Krauss
Publication year - 2021
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.108588
Subject(s) - microbiology and biotechnology , axonal degeneration , degeneration (medical) , axotomy , mitochondrion , biology , phenotype , axon , small molecule , central nervous system , neuroscience , biochemistry , pathology , gene , medicine
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom