Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
Author(s) -
Jasper E. Neggers,
Brenton R. Paolella,
Adhana Asfaw,
Michael Rothberg,
Thomas A. Skipper,
Annan Yang,
Radha L. Kalekar,
John M. Krill-Burger,
Neekesh V. Dharia,
Guillaume Kugener,
Jérémie Kalfon,
Chen Yuan,
Nancy Dumont,
Alfredo González,
Mai Abdusamad,
Yvonne Y. Li,
Liam F. Spurr,
Westley W. Wu,
Adam D. Durbin,
Brian M. Wolpin,
Federica Piccioni,
David E. Root,
Jesse S. Boehm,
Andrew D. Cherniack,
Aviad Tsherniak,
Andrew L. Hong,
William C. Hahn,
Kimberly Stegmaier,
Todd R. Golub,
Francisca Vázquez,
Andrew J. Aguirre
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.108493
Subject(s) - biology , escrt , vacuolar protein sorting , rna interference , synthetic lethality , gene , genetics , cancer research , microbiology and biotechnology , endosome , dna repair , rna , cell , mutant
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