Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen
Author(s) -
Haofei Wang,
Tushar Warrier,
Chadi El Farran,
Zihao Zheng,
Q. Xing,
Melissa J. Fullwood,
LiFeng Zhang,
Hu Li,
Jian Xu,
T. M. Lim,
YuinHan Loh
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.108309
Subject(s) - crispr , enhancer , cas9 , biology , induced pluripotent stem cell , embryonic stem cell , gene , computational biology , genome editing , microbiology and biotechnology , genetics , crispr interference , stem cell , gene expression
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