Open AccessMn2+ Directly Activates cGAS and Structural Analysis Suggests Mn2+ Induces a Noncanonical Catalytic Synthesis of 2′3′-cGAMP
Author(s) -
Zhen Zhao,
Zhixing Ma,
Bo Wang,
Yukun Guan,
XiaoDong Su,
Zhengfan Jiang
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.108053
Subject(s) - chemistry , stereochemistry , dna , catalysis , activator (genetics) , moiety , cofactor , cytosol , microbiology and biotechnology , biochemistry , receptor , enzyme , biology
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