Open AccessInhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer
Author(s) -
Aria Vaishnavi,
Michael T. Scherzer,
Conan G. Kinsey,
Gennie L. Parkman,
Amanda Truong,
Phaedra C. Ghazi,
Sophia Schuman,
Benjamin Battistone,
Ignacio GarridoLaguna,
Martin McMahon
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.107994
Subject(s) - cancer research , mek inhibitor , pancreatic cancer , tropomyosin receptor kinase a , gene silencing , in vivo , kinase , receptor tyrosine kinase , mapk/erk pathway , cancer , biology , medicine , receptor , microbiology and biotechnology , nerve growth factor , gene , biochemistry
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