Open AccessThe Ubiquitin Ligase TRIP12 Limits PARP1 Trapping and Constrains PARP Inhibitor Efficiency
Author(s) -
Marco Gatti,
Ralph Imhof,
Qingyao Huang,
Michael Baudis,
Matthias Altmeyer
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.107985
Subject(s) - parp1 , dna damage , ubiquitin ligase , poly adp ribose polymerase , cancer research , biology , dna repair , parp inhibitor , synthetic lethality , ubiquitin , microbiology and biotechnology , genome instability , dna ligase , chemistry , genetics , dna , polymerase , gene
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