Open AccessLow-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
Author(s) -
Irem OzkanDagliyan,
J. Nathaniel Diehl,
Samuel D. George,
Antje Schaefer,
Bjoern Papke,
Kathleen KlotzNoack,
Andrew M. Waters,
Craig M. Goodwin,
Prson Gautam,
Mariaelena Pierobon,
Sen Peng,
Thomas S.K. Gilbert,
Kevin Lin,
Onur Dağliyan,
Krister Wennerberg,
Emanuel F. Petricoin,
Nhan L. Tran,
Shripad V. Bhagwat,
Ramón V. Tiu,
Sheng-Bin Peng,
Laura E. Herring,
Lee M. Graves,
Christine Sers,
Kris C. Wood,
Adrienne D. Cox,
Channing J. Der
Publication year - 2020
Publication title -
cell reports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 6.264
H-Index - 154
eISSN - 2639-1856
pISSN - 2211-1247
DOI - 10.1016/j.celrep.2020.107764
Subject(s) - kras , apoptosis , mapk/erk pathway , mutant , cancer research , mek inhibitor , chemistry , biology , mutation , kinase , microbiology and biotechnology , genetics , gene
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